Endocrine Abstracts

Background & objectives: There are multiple forms of functional TSHR autoantibodies which stimulate or inhibit the thyroid. The TSH-Receptor blocking antibody (TSBAb) exists in the serum of Graves’ disease, which is functionally different from TSH receptor stimulating antibody (TSAb). TSBAb that blocks the action of TSH is also associated with idiopathic myxedema and some Hashimoto’s disease. We measured TSBAb levels and evaluated the pathogenetic significance of...